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MULTIPLE SCLEROSIS and L-Carnitine is an amino acid that is involved in energy production and neurological function. One particular form, "Acetyl L-Carnitine" seems to be better absorbed and utilized by the brain and nerves. It is also usually more expensive.
ANTIOXIDANT Acetyl L-Carnitine can function as an antioxidant to protect myelin and nerve cells from free-radical damage. Taking it with Coenzyme-10 may improve this activity BLOOD SUPPLY / MEMORY / NEUROTRANSMITTERS These three benefits of Acetyl L-Carnitine may be interrelated. Improved blood flow to the brain can help the neurons use the available nutrients for efficiently and eliminate waste products more completely. This could help protect and regrow myelin. It also would improve the ability of the neuron to conduct impulses. Even when myelin has been lost, nerves are still capable of conducting impulses. However, this process is much slower and less accurate that when the nerve is protected by myelin. Acetyl L-Carnitine is similar is structure to Acetylcholine, one of the important chemicals used by the brain and nerves to transmit impulses (neurotransmitters). Acetylcholine is involved in memory and learning. It has also been reported that Acetyl L-Carnitine can increase the activity of Dopamine, another brain neurotransmitter. CAUTIONS Because of the increase in brain activity it can cause, Acetyl L-Carnitine may cause sleep problems if taken too late in the evening. Some authors recommend avoiding it if you have any seizure disorder. DOSAGE Dosages range from 500 mg per day up to 3000 mg (3 grams) daily. |